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ADHD Medication During Pregnancy and Breastfeeding The choice of whether to stop or continue ADHD medication during pregnancy and nursing is a difficult decision for women suffering from the condition. There aren't many studies on how long-term exposure may affect a fetus. A recent study published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological issues such as impaired hearing or vision, febrile seizures, or IQ impairment. The authors acknowledge that further high-quality research is needed. Risk/Benefit Analysis Women who are pregnant and take ADHD medication should evaluate the benefits of using it against the possible risks for the fetus. The doctors don't have the information to make unambiguous recommendations, but can provide information on the risks and benefits to aid pregnant women in making an informed decision. A study published in Molecular Psychiatry concluded that women who took ADHD medication in early pregnancy did not have a higher risk of fetal malformations or structural birth defects. Researchers used a vast population-based case-control study to evaluate the incidence of major structural birth defects in infants born to mothers who had taken stimulants during the early stages of pregnancy and those who had not. Clinical geneticists and pediatric cardiologists reviewed the cases to ensure an accurate case classification and to minimize the chance of bias. However, the researchers' study had its limitations. Researchers were unable, in the first place to differentiate the effects triggered by the medication from the disorder. That limitation makes it difficult to know whether the limited associations observed in the groups that were exposed are due to medication use or the confounding effect of comorbidities. Additionally the study did not study long-term offspring outcomes. The study did find that infants whose mothers took ADHD medications during pregnancy were at a greater risk of being admitted to the neonatal intensive care unit (NICU) than infants who whose mothers did not take any medication or had taken off their medication prior to or during pregnancy. The reason for this was central nervous system-related disorders, and the increased risk for admission was not found to be influenced by which stimulant medications were taken during pregnancy. Women who were taking stimulant ADHD medications during pregnancy also had a higher chance of having to have an emergency caesarean section or having a baby that scored low on the Apgar scale (less than 7). These increases appear to be unrelated to the type of medication taken during pregnancy. Researchers suggest that the minor risk of using ADHD medications during early pregnancies may be offset by the more beneficial outcomes for both mother and baby from continuing treatment for the woman’s disorder. Doctors should discuss with their patients about this issue and as much as possible, assist them improve coping skills which can lessen the effects of her disorder on her daily functioning and her relationships. Medication Interactions Many doctors are faced with the decision of whether to keep treatment or stop during pregnancy as more women are diagnosed with ADHD. Most of the time, these decisions are made without clear and authoritative evidence either way, so physicians must weigh their knowledge, the experiences of other doctors, and what research says on the topic as well as their best judgment for each individual patient. In particular, the issue of potential risks to the baby can be a challenge. Many of the studies on this issue are based on observational data rather than controlled research and their conclusions are often contradictory. Furthermore, most studies restrict their analysis to live births, which may underestimate the severity of teratogenic effects that could result in abortion or termination of the pregnancy. The study discussed in the journal club addresses these shortcomings by analyzing both information on deceased and live births. Conclusion Some studies have found an association between ADHD medications and certain birth defects however, other studies haven't established a link. Most studies show an unintended, or slightly negative, effect. In the end, a careful risk/benefit assessment must be conducted in every instance. It can be difficult, if not impossible, for women with ADHD to stop taking their medication. In a recent article published in the Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can increase depression and feelings of isolation. A loss of medication may also impact the ability to drive safely and complete work-related tasks, which are crucial aspects of normal life for those suffering from ADHD. She suggests that women who aren't sure whether to take the medication or stop it due to their pregnancy should educate family members, coworkers, and friends about the condition, its effects on daily functioning, and the advantages of staying on the current treatment. It can also make the woman feel more comfortable in her struggle with her decision. Certain medications can be passed through the placenta. If the patient decides to not take her ADHD medication while pregnant and breastfeeding, it is important to be aware that the drug could be passed on to her baby. Risk of Birth Defects As the use and use of ADHD medication to treat symptoms of attention deficit hyperactivity disorder (ADHD) is increasing as does the concern about the potential effects of these drugs on foetuses. A study that was published in the journal Molecular Psychiatry adds to the body of knowledge on this subject. Using two massive data sets, researchers were able to examine more than 4.3 million pregnancies and see whether stimulant medication use increased the risk of birth defects. Although the risk overall remains low, the researchers did find that first-trimester exposure to ADHD medications was linked to an increased risk of certain heart defects such as ventriculoseptal defect (VSD). The researchers of the study did not discover any link between early use of medication and other congenital anomalies such as facial deformities or club feet. The results are in the same vein as previous studies that have shown an insignificant, but small increase in cardiac malformations for women who started taking ADHD medication prior to the time of pregnancy. This risk increased in the later part of pregnancy, when a lot of women decide to stop taking their ADHD medication. adhd adults medication who used ADHD medications during the first trimester of their pregnancy were also more likely to undergo caesarean sections, a low Apgar score following delivery, and a baby who needed breathing assistance during birth. The researchers of the study were not able to eliminate selection bias because they limited their study to women without other medical conditions that might have contributed to the findings. The researchers hope their study will serve to inform the clinical decisions of physicians who encounter pregnant women. They recommend that, while a discussion of the risks and benefits is crucial but the decision to stop or continue treatment should be based on the woman's requirements and the severity of her ADHD symptoms. The authors also caution that even though stopping the medication is an option, it isn't an option that is recommended due to the high incidence of depression and other mental health issues among women who are pregnant or recently post-partum. Additionally, research suggests that women who stop taking their medication will have a tough time adjusting to a life without them once the baby is born. Nursing It can be a challenge to become a mom. Women with ADHD are often faced with a number of difficulties when they must manage their symptoms, go to doctor appointments, prepare for the birth of their child and adjust to a new routine. Many women opt to continue taking their ADHD medication during pregnancy. The majority of stimulant medications are absorbed by breast milk in low amounts, therefore the risk to the infant who is breastfeeding is low. However, the rate of exposure to medications by the infant can differ based on dosage, frequency it is administered, and the time of day it is administered. Additionally, different medications enter the body of the baby differently through the gastrointestinal tract as well as breast milk and the impact of this on a newborn isn't yet fully known. Due to the absence of research, some physicians might be tempted to stop taking stimulant medication during a woman's pregnancy. This is a difficult choice for the patient, who must balance the benefits of keeping her medication against the potential dangers to the embryo. As long as there is no more information, doctors should ask all pregnant patients about their experience with ADHD and whether they plan or are taking to take medication during the perinatal time. A growing number of studies have revealed that most women can safely continue to take their ADHD medication during pregnancy and breastfeeding. In response, a rising number of patients are choosing to do this. They have found, in consultation with their doctor, that the benefits of retaining their current medication outweigh any risk. It's important for women with ADHD who are thinking of breastfeeding to seek a specialist psychiatrist's advice prior to becoming pregnant. They should discuss their medication with their doctor as well as the pros and cons for continuing treatment. This includes non-pharmacological strategies. Psychoeducation is also necessary to help pregnant women with ADHD recognize the signs and underlying disorder. They should also learn about treatment options and build strategies for coping. This should be a multidisciplinary effort with the GPs, obstetricians, and psychiatrists. Pregnancy counseling should include a discussion of a treatment plan for the mother and child, and monitoring for signs of deterioration and, if necessary adjustments to the medication regime.